Background Immune checkpoint blockers (ICBs) have been approved by the Food and Drug Administration to be used alone in front-line therapies or in combination with other regimens for certain advanced cancers.Since ICB only works in a subset of patients and has limited efficacy in treating ovarian cancer (OVC), developing preclinical models that hel
The prediction and control of vortex-induced vibration (VIV) is one of the key problems for riser design.The effect of platform heave motion on VIV of deep sea top-tensioned riser (TTR) is presented by means of numerical simulation and experiment in this research.First, the heave motion was modeled as a parametric excitation, and the governing equa
Information centric networking (ICN) shifts the focus of existing internet architecture from host-oriented to content-oriented model by enabling in-network caching and content-based forwarding.These ICN features help to increase network performance Tool Boxes by decreasing content discovery delay, content server load, and network congestion.To rout
The results of the monitoring of three VLF/LF signals collected in Petropavlovsk station (Kamchatka, Russia) and one VLF signal collected on board of the DEMETER French satellite are presented.Two periods of the seismic activity occurred in the Japan-Kamchatka area during November–December 2004 and July–September 2005 were inves
The objective of this study was to evaluate ingredients and diets containing increasing levels of crambe cake protein replacing soybean meal protein, with in vitro ruminal fermentation parameters using a gas production technique.Diets were formulated for feedlot lambs and contained different levels of crambe cake protein (0, 250, 500, 750, and 1000